Peripheral nerve tumors are relatively uncommon and occur less than 5% in all the tumors of the hand. If asymptomatic, diagnosis is typically made intraoperatively or on histological review. Therefore, preoperative diagnosis and a basic knowledge of peripheral nerve tumors is important to avoid mismanagement that can result in a poor outcome. We review a series of cases examining clinical presentation, diagnostic studies, surgical management, and outcome. A review of the literature compliments this experience. With that knowledge we provide an overview to peripheral nerve tumors of the upper extremity including clinical presentation, differential diagnosis, preoperative evaluation, surgical methods, pathology, and expected outcome.