Compression neuropathy of the lower extremity is a relatively common disease at the spinal root and tarsal tunnel levels. However, compression neuropathy of the sciatic nerve is rare. We present the case of a 50 year-old woman who ruptured the origin of her left hamstring during a fall. The patient complained of numbness of her posterior thigh and weakness of her leg musculature. Her signs and symptoms persisted for nine months despite physical therapy. After nine months of therapy without improvement, the patient underwent an EMG/NCS, which showed sciatic neuropathy 21 cm proximal to the popliteal crease. This location coincided with an area of scarred muscle that was visualized on an MRI obtained seven months after injury. The patient underwent surgical decompression of the nerve shortly after her EMG. Intraoperative EMG showed immediate improvement in conduction following decompression. The patient has markedly improved since the operation. When posttraumatic weakness involves multiple muscles supplied by the same motor nerve, the possibility of nerve compression should be investigated. Even though nerve compression is a rare diagnosis, it must be considered, especially in the sports medicine setting. Review of the literature demonstrates similar occurrences in the common peroneal nerve after gastrocnemius rupture and the posterior tibial nerve after popliteus rupture. An EMG/NCS can provide valuable information as to whether nerve compression is present. Earlier intervention will lead to decreased muscle atrophy, more rapid functional recovery, and decreased time of patient suffering.